Viagra Frisky Might Be Melanoma Risky

Many who knows about positive effects of the famous brand Viagra. Nevertheless, some people do not know all the consequences from the treatment with this remedy. It induces some unpleasant health complications. The list of them can be reviewed in any guide of the remedy. However, there are some other hidden risks, which are associated with the treatment with Viagra.

One of such possibilities is melanoma. Some trials and clinical test assure that individuals who implement this remedy are greatly predisposed for receiving melanoma. This is the most dangerous form of skin cancer. The potential risk for falling ill with this ailment if curing with Viagra is 84%.

However, the true evidence is not defined, but the potential risk really exists. There are still multiple debates concerning this issue. It is proven that there is no connection between ED and this type of cancer. Still, there is an explanation why Sildenafil (the main constituent) may be a reason for this severe ailment.

It belongs to the family of PDE-5 inhibitors, which enable the occurrence of erection. Simultaneously, it activates such genes as BRAF and NRAS. These can induce melanoma. This inhibitor stimulates synthesis of genes that lead to cancer development.

What Is Melanoma?

This is an utterly severe disease, which can lead to the most grievous outcomes. It is the most serious form of skin cancer. It is easier to prevent the disease, than to get rid of it. It can affect people of different races, ages and genders. Conventionally, it develops from melanocytes of normal skin and pigmented nevi. Its growth is quite fast. Frequently, it affects not only skin, but also bones and organs.

Fortunately, this is a rare ailment. It reaches about 1% of all tumors of this classification. It strikes people aged 30-40 years. Most part of whom are women. However, it can affect even children.

The reasons for the forming of the ailment are:

• ultraviolet rays (though it occurs in regions where bodies of the inhabitants are mostly covered with clothing);
• sunburns (oftentimes received in childhood);
• mechanical trauma of moles (the potential risk ranges from 30 to 85%);
• electromagnetic radiation (in most cases it strikes people who work with electronics or who are connected with dyes, plastic, rubber, vinyl and something of the kind);
• the administration of medical preparations, contraception and estrogen cures that are directed to resolve vegetative disorders during menopauses and menstrual disorders;
• inappropriate nutrition (overly high consumption of proteins and animal fat, low usage of vegetables and fruits that contain vitamins C and A);
• systematic and abnormal usage of alcohol.

This list shows that one of the possible reasons of this ailment is usage of medical preparations. Generic Viagra and similar to it preparations may provoke melanoma.

Detailed Research

A study showed that men who implemented Sildenafil had twice the risk for having this ailment in comparison to those who never took it. The study involved 26,000 participants. Jiali Han, PhD, of the Indiana University School of Public Health in Indianapolis, and other scholars, conducted it.

The scholars cannot prove the reason and effect and require further researches that would take into account doses and frequency of usage. Nevertheless, there was a confirmation of potential risks. There is no molecular connection of PDE5 inhibitor and the tumor. However, it can promote the development of the tumor in tumor cells. Under condition, the research would prove the real evidence the scholars believe that the entire class of PDE5 inhibitors should be added to the list of causes for this ailment. Find out about use of PDE5 Inhbitors here: http://www.ncbi.nlm.nih.gov/pubmed/15224127

The researches compiled the data from the earliest researches, which were dated even in the middle of 80-ies and 90-ies. They tried to include all possible factors and asked the participants whether they undergone surgery or other treatment for erectile dysfunction. However, the surveys did not include the indications of doses and frequency of usage. The questionnaires also took into account all possible risk factors that can induce melanoma.

The men who undergone the course of treatment with Sildenafil were commonly of older age, had serious sunburns in history, had physical examinations and some other essential factors. The final outcomes showed unfortunate tendency for the enhancement of probable risks for this ailment.

Of course, evidence that is more dependable has to clarify the whole situation. Nevertheless, the current proofs are undeniable. The usage of Sildenafil and possibly, other inhibitors of this series, enhances the chances for receiving melanoma. Consequently, all users of Viagra and similar preparations should add this risk factor to the common list of possible diseases and disorders.

https://www.canadianhealthmall.com – Canadian Pharmacy Team